Correct Answer: D

Rationale: The primary function of the liver is to detoxify harmful substances in the body. While the liver does produce bile to aid in the digestion of fats, this is not its primary function. Bile is stored in the gallbladder and released into the small intestine for fat digestion. Storing energy in the form of glycogen is a function of the liver, but not its primary one. Glycogen serves as a reserve of glucose. Although the liver produces proteins that assist in blood clotting, such as fibrinogen and prothrombin, this is not its main function. These proteins play a crucial role in blood clotting to prevent excessive bleeding. Therefore, the primary role of the liver is to detoxify harmful substances by processing and removing toxins, drugs, alcohol, and other harmful substances from the bloodstream, thereby reducing their harmful effects.

Correct Answer: D

Rationale: A) Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset: Proper attachment of chromosomes to spindle fibers is essential for accurate segregation of genetic material during cell division. Misaligned chromosomes that fail to attach to microtubules can lead to delays in anaphase onset, allowing the cell to correct errors before proceeding with division. B) The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression: Kinetochores at the centromeres help attach chromosomes to spindle fibers. When kinetochores are unattached or improperly attached to microtubules, they signal the cell to pause cell cycle progression, ensuring proper chromosome alignment before division. C) Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins: While microtubule dynamics are crucial for cell division, microtubule instability and rapid depolymerization can disrupt chromosome attachment. However, this mechanism is not directly related to the activation of cell cycle checkpoint proteins, making this statement incorrect. Therefore, choices A and B accurately describe how spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints, making option D the correct answer.

Correct Answer: B

Rationale: The correct answer is B: Thoracic duct. The thoracic duct is the largest lymphatic vessel in the body and is responsible for draining lymph from most of the body. The jugular vein, subclavian vein, and aorta are not lymphatic vessels responsible for draining lymph. The jugular vein and subclavian vein are blood vessels, while the aorta is the main artery that carries oxygenated blood from the heart. Understanding the role and anatomy of the lymphatic system is crucial for comprehending the body's immune response and fluid balance.

Correct Answer: D

Rationale: SOCl2 (thionyl chloride) is commonly used to convert primary alcohols to alkyl halides through an SN2 mechanism. Thionyl chloride reacts with the alcohol to form an alkyl chloride. HI (hydroiodic acid) is typically used to convert alcohols to alkyl iodides specifically, not alkyl halides in general. H2O (water) and NaOH (sodium hydroxide) are not reagents used for converting alcohols to alkyl halides. Therefore, the correct answer is SOCl2 as it facilitates the conversion of primary alcohols to alkyl halides, unlike the other options provided.

Correct Answer: B

Rationale: A) Trait: A trait is a characteristic or feature of an organism that is determined by its genes. B) Mutation: A mutation is a permanent alteration in the DNA sequence that can result from errors during DNA replication, exposure to mutagens, or other factors. C) Allele: An allele is a variant form of a gene that can result in different traits or characteristics. D) Variation: Variation refers to the differences in traits or characteristics among individuals of the same species, which can be influenced by genetic and environmental factors. In this context, the term that specifically refers to a permanent alteration in the DNA sequence is "mutation."