HESI RN
HESI RN Patho Pharmacology Questions
Extract:
Question 1 of 5
Three days after a cholecystectomy for cholelithiasis, a client reports persistent upper abdominal pain that radiates to the back. The client has vomited three times in the last 12 hours and has a temperature of 101.8° F (38.7° C). Serum amylase and lipase are twice the normal value. Based on these findings, the nurse should observe the client for which pathophysiological condition?
Correct Answer: A
Rationale: Elevated amylase/lipase, pain radiating to the back, vomiting, and fever suggest acute pancreatitis (
A), possibly triggered by gallstones. Surgical site infection (
B) lacks pancreatic markers. Hepatorenal failure (
C) involves kidney/liver dysfunction. Biliary obstruction (
D) may elevate bilirubin, not amylase.
Question 2 of 5
A client who has asthma (a reactive airway disease) asks the nurse about the role of leukotrienes in this process. Leukotrienes have which immune response?
Correct Answer: B
Rationale: Leukotrienes cause bronchoconstriction and mucus production (
B) in asthma, worsening airway obstruction. Itching (
A) is histamine-mediated. Bradykinin (
C) is unrelated to leukotrienes. Leukotrienes act via receptors, not as antigen receptors (
D).
Question 3 of 5
The nurse is caring for a school-aged child with Burkitt lymphoma. A review of the child’s laboratory results reveal serum calcium 8.1 mg/dL (1.9 mmol/L), serum potassium 6.1 mEq/L (6.1 mmol/L), and serum phosphorus 5.9 mg/dL (3.6 mmol/L). Which pathophysiological process is associated with the child’s laboratory results?
Correct Answer: B
Rationale: Tumor lysis syndrome (
B) causes hyperkalemia (potassium 6.1 mEq/L) and hyperphosphatemia (phosphorus 5.9 mg/dL) from rapid cancer cell breakdown, common in Burkitt lymphoma. Hypocalcemia (calcium 8.1 mg/dL) also occurs. Wilms tumor (
A) affects kidneys. Superior vena cava syndrome (
C) causes swelling. Hyperleukocytosis (
D) involves high WBCs.
Question 4 of 5
The nurse is caring for a young adult who reports uncontrolled acne vulgaris. Which pathological findings should the nurse observe on inspection of skin areas commonly affected in acne vulgaris?
Correct Answer: C
Rationale: This question is identical to Question 10. Acne vulgaris causes comedones, papules, and pustules from sebaceous hyperactivity (
C) on face/neck/back. Skin tags (
A) are benign. Hyperpigmentation (
B) follows acne. Scaling plaques (
D) indicate psoriasis. Note: Duplicate question; consider removing.
Question 5 of 5
The nurse is providing care for a client with a diagnosis of otosclerosis due to previous ear surgeries. Which type of pathological hearing loss supports the client’s clinical history?
Correct Answer: B
Rationale: Otosclerosis causes conductive hearing loss (
B) by immobilizing the stapes, impairing sound transmission. Presbycusis (
A) is age-related sensorineural loss. Endolymphatic (
C) relates to Ménière’s disease. Sensorineural loss (
D) involves inner ear/nerve damage.