HESI RN
HESI RN D441 Pharmacology 0A1 Questions
Question 1 of 5
The nurse is teaching a client who has been diagnosed with human immunodeficiency virus (HIV) about the antiretroviral medication regimen. Which statement provided by the client requires additional instruction by the nurse?
Correct Answer: D
Rationale: While antiretroviral therapy (ART) significantly reduces HIV transmission risk by lowering viral load, it does not completely prevent it. The client needs clarification that even with an undetectable viral load, transmission is possible, and preventive measures like safer sex practices are still necessary.
Question 2 of 5
Which action should the nurse implement to assess the effectiveness of amlodipine?
Correct Answer: C
Rationale: Amlodipine, a calcium channel blocker, is used to manage hypertension. Measuring blood pressure directly assesses its effectiveness in lowering blood pressure, the primary therapeutic goal.
Question 3 of 5
The healthcare provider prescribes propylthiouracil (PTU) and Lugol's solution, a strong iodine solution, for a client with hyperthyroidism. How should the nurse schedule the administration of these medications?
Correct Answer: D
Rationale: Administering Lugol's solution one hour before PTU allows iodine to suppress thyroid hormone release before PTU takes effect, enhancing therapeutic outcomes in hyperthyroidism. PTU should be taken on an empty stomach, and the medications should not be given together or at bedtime without specific timing considerations.
Question 4 of 5
A client receives a prescription for ciprofloxacin 400 mg intravenously (IV) every 12 hours to be infused over an hour. The IV bag contains ciprofloxacin 400 mg in dextrose 5% in water (DW) 200 mL. The nurse should program the infusion pump to deliver how many mL/hr? (Enter numerical value only.)
Correct Answer: 200
Rationale: The IV bag contains 200 mL of solution to be infused over 1 hour. Infusion rate =
Total volume (mL) / Infusion time (hours) = 200 mL / 1 hour = 200 mL/hr.
Question 5 of 5
A client who received a renal transplant three months ago is readmitted to the acute care unit with signs of graft rejection. While taking the client's history, the nurse determines that the client has been self-administering St. John's Wort, an herbal preparation, on the advice of a friend. Which information is most significant about this finding?
Correct Answer: A
Rationale: St. John's Wort induces liver enzymes, reducing cyclosporine levels, an immunosuppressant critical for preventing transplant rejection. This interaction increases the risk of graft rejection, making it the most significant finding requiring immediate attention.