HESI RN
HESI RN Patho Pharmacology Questions
Extract:
Question 1 of 5
A male client with type 1 diabetes mellitus (DM) develops a gangrenous toe and is admitted for possible amputation. Which pathophysiological consequence of DM has contributed to this client’s complication?
Correct Answer: C
Rationale: Peripheral neuropathy (
C) from prolonged hyperglycemia damages sensory nerves, reducing pain perception and leading to unnoticed foot injuries, infections, and gangrene. CKD (
A) affects kidneys, not directly causing gangrene. Retinopathy (
B) impacts eyes. Hypertension (
D) exacerbates vascular issues but is secondary to neuropathy in this context.
Question 2 of 5
The nurse is explaining the underlying cause of bruising with a client who is recently diagnosed with acute leukemia. Which pathophysiology is a result of the myeloblastic dysfunction of leukemia?
Correct Answer: B
Rationale: Leukemia causes thrombocytopenia (insufficient platelets) (
B), delaying clotting and causing bruising. Oxyhemoglobin (
A) relates to oxygen transport. Phagocytic cell deficiency (
C) increases infection risk. Iron deficiency (
D) causes anemia, not bruising.
Question 3 of 5
When planning care for a client who is diagnosed with a large abdominal aortic aneurysm (AAA), the nurse should carefully monitor for which signs and symptoms?
Correct Answer: A
Rationale: AAA rupture causes flank pain and hypotension (
A) from internal bleeding. Shortness of breath and chest pain (
B) suggest thoracic issues. Absent pulses/darkened toes (
C) indicate peripheral ischemia, not AAA. Tea-colored urine (
D) suggests kidney injury, not primary AAA signs.
Question 4 of 5
A client with end stage emphysema is experiencing poor gas exchange. Which respiratory structure is associated with the pathophysiological processes in emphysema?
Correct Answer: D
Rationale: Emphysema involves alveolar wall destruction (
D), reducing gas exchange surface area, causing hypoxemia. Bronchioles (
A) are affected in asthma/bronchitis. Trachea (
B) is a conduit. Bronchi (
C) are involved in bronchitis, not emphysema.
Question 5 of 5
During an interview with a male client who has Parkinson’s disease (PD), the nurse notices that he is drooling and mumbling. Which pathophysiological factor contributes to the client’s inability to express himself?
Correct Answer: B
Rationale: PD involves degeneration of dopaminergic neurons in the basal ganglia (
B), causing motor symptoms like bradykinesia and rigidity, impairing speech. Broca’s area damage (
A) causes aphasia, not PD-related. Amyloid plaques (
C) indicate Alzheimer’s. Pharyngeal paralysis (
D) causes dysphagia, not speech issues.