HESI RN
Nightdale College HESI Pharmacology RN Questions
Extract:
Question 1 of 5
The nurse is planning care for a client with major depression who is receiving a new prescription for duloxetine. Which information is most important for the nurse to obtain? Which information is most important for the nurse to obtain?
Correct Answer: B
Rationale: Duloxetine is metabolized by the liver, and hepatotoxicity is a rare but serious risk. Obtaining liver function test results is critical to ensure safe administration, as impaired liver function increases the risk of toxicity. Other factors like weight changes or antidepressant use are relevant but secondary to liver function.
Question 2 of 5
A client taking atorvastatin develops an increased serum creatine phosphokinase (CK) level. The nurse should assess the client for the onset of which problem? Which problem should the nurse assess the client for the onset of?
Correct Answer: A
Rationale: Elevated CK levels indicate muscle damage, a sign of myopathy, a rare but serious side effect of atorvastatin. Assessing for muscle tenderness is critical to detect myopathy early, which can progress to rhabdomyolysis if untreated. Other symptoms like nausea or bruising are not directly related to CK elevation.
Question 3 of 5
The nurse is planning to administer the antiulcer gastrointestinal (GI) agent sucralfate to a client with peptic ulcer disease. Which action should the nurse include in this client's plan of care? Which action should the nurse include in this client's plan of care?
Correct Answer: B
Rationale: Sucralfate forms a protective barrier over ulcers in an acidic environment, requiring administration on an empty stomach, one hour before meals or at bedtime. Once-daily dosing is insufficient, and electrolyte imbalances or Candida infections are not primary concerns with sucralfate.
Question 4 of 5
A client is receiving intravenous (IV) vancomycin and the nurse plans to draw blood for a peak and trough to determine the serum level of the medication. Which of the following collection times provide the best determination of these levels? Which collection times provide the best determination of these levels?
Correct Answer: B
Rationale: Peak vancomycin levels, reflecting maximum concentration, are best measured one hour after IV dose completion. Trough levels, indicating minimum concentration, are drawn one hour before the next dose. This timing ensures accurate monitoring of therapeutic levels and prevents toxicity.
Question 5 of 5
The nurse admits a client with a diagnosis of stage 4 cancer. The client has a prescription to wear a subcutaneous morphine sulfate patch for pain. The client is short of breath and difficult to arouse. While performing a head to toe assessment, the nurse discovers four patches on the client's body. Which action should the nurse take first? Which action should the nurse take first?
Correct Answer: B
Rationale: Multiple morphine patches indicate an overdose, causing respiratory depression and sedation. Removing the patches stops further drug absorption, addressing the root cause. Oxygen or reversal drugs may follow, but removing the source is the priority to prevent worsening of the overdose.