HESI RN
RN HESI Pharmacology Exam 3 Questions
Extract:
Question 1 of 5
A client who received a renal transplant three months ago is readmitted to the acute care unit with signs of graft rejection. While taking the client's history, the nurse determines that the client has been self-administering St. John's Wort, an herbal preparation, on the advice of a friend. Which information is most significant about this finding?
Correct Answer: D
Rationale: St. John's Wort induces liver enzymes (CYP3A4), reducing cyclosporine levels, an immunosuppressant critical for preventing transplant rejection. This interaction increases rejection risk, making it the most significant finding. Corticosteroid needs, depression, or sodium intake are less critical.
Question 2 of 5
A glucagon emergency kit is prescribed for a client with type 1 diabetes mellitus. When should the nurse instruct the client and family that glucagon needs to be administered?
Correct Answer: C
Rationale: Glucagon raises blood glucose in severe hypoglycemia (e.g., unconsciousness), preventing complications. It’s not for hyperglycemia, sick days, or diabetic ketoacidosis, which require insulin and other treatments.
Question 3 of 5
A client who is taking furosemide reports experiencing leg cramps, a cough, feeling tired, and palpitations. Which action should the nurse take first?
Correct Answer: A
Rationale: Furosemide can cause hypokalemia, leading to palpitations and cramps, risking arrhythmias. Cardiac monitoring first detects potential arrhythmias, prioritizing safety. Intake/output, compresses, or bed elevation are secondary to addressing cardiac risks.
Question 4 of 5
The nurse is caring for a client receiving a prescription for sucralfate to treat a peptic ulcer. Which instruction should the nurse provide during discharge education?
Correct Answer: C
Rationale: Sucralfate adheres to ulcer sites best on an empty stomach, taken 1 hour before meals, maximizing its protective effect. Missing a dose should not prompt doubling, and scheduling with meals or bedtime reduces efficacy due to food interference.
Question 5 of 5
A client receives a prescription for ciprofloxacin 400 mg intravenously (IV) every 12 hours to be infused over an hour. The IV bag contains ciprofloxacin 400 mg in dextrose 5% in water (D5W) 200 mL. The nurse should program the infusion pump to deliver how many mL/hr? (Enter numerical value only.)
Correct Answer: 200
Rationale: Infusion rate = 200 mL ÷ 1 hour = 200 mL/hr. The pump should be set to deliver 200 mL/hr to infuse the entire dose over one hour.