HESI RN
Nightdale College HESI Pharmacology RN Questions
Extract:
Question 1 of 5
A client who received a renal transplant three months ago is readmitted to the acute care unit with signs of graft rejection. While taking the client's history, the nurse determines that the client has been self-administering St. John's Wort, an herbal preparation, on the advice of a friend. Which information is most significant about this finding? Which information is most significant about this finding?
Correct Answer: A
Rationale: St. John’s Wort induces liver enzymes, reducing cyclosporine levels, an immunosuppressant critical for preventing transplant rejection. This interaction is the most significant, as it directly contributes to graft rejection. Other options, like depression treatment or sodium intake, are less relevant to the acute issue.
Question 2 of 5
A client who is taking an oral contraceptive receives a new prescription for erythromycin. Which instruction should the nurse provide to the client? Which instruction should the nurse provide to the client?
Correct Answer: D
Rationale: Erythromycin can reduce oral contraceptive efficacy by increasing metabolism. Using an additional contraceptive method, like condoms, prevents unintended pregnancy during and after the antibiotic course. Stopping the contraceptive or timing doses apart is not effective, and photosensitivity is not a concern with erythromycin.
Question 3 of 5
A client with hepatic encephalopathy is receiving lactulose. Which assessment provides the nurse with the best information to evaluate the client's therapeutic response to the drug? Which assessment provides the best information to evaluate the client's therapeutic response to the drug?
Correct Answer: B
Rationale: Lactulose lowers blood ammonia levels by promoting its excretion in stool, treating hepatic encephalopathy. Monitoring serum ammonia and electrolytes (due to potential loss from diarrhea) directly evaluates the drug’s effectiveness. Stool changes are expected but less specific, and hepatic enzymes or glucose are not primary indicators.
Question 4 of 5
The nurse administers risedronate to a client with osteoporosis at 0700. The client asks for a glass of milk to drink with the medication. Which action should the nurse take? Which action should the nurse take?
Correct Answer: A
Rationale: Risedronate, a bisphosphonate, requires administration with water on an empty stomach to ensure absorption, as calcium in milk binds to the drug, reducing efficacy. Instructing the client to take it with water only is critical. Delaying or taking with food/milk is incorrect and reduces effectiveness.
Question 5 of 5
The nurse admits a client with a diagnosis of stage 4 cancer. The client has a prescription to wear a subcutaneous morphine sulfate patch for pain. The client is short of breath and difficult to arouse. While performing a head to toe assessment, the nurse discovers four patches on the client's body. Which action should the nurse take first? Which action should the nurse take first?
Correct Answer: B
Rationale: Multiple morphine patches indicate an overdose, causing respiratory depression and sedation. Removing the patches stops further drug absorption, addressing the root cause. Oxygen or reversal drugs may follow, but removing the source is the priority to prevent worsening of the overdose.