HESI RN
HESI Pharmacology Questions
Extract:
Question 1 of 5
A client who received a renal transplant three months ago is readmitted to the acute care unit with signs of graft rejection. While taking the client’s history, the nurse determines that the client has been self-administering St. John's Wort, an herbal preparation on the advice of a friend. Which information is most significant about this finding?
Correct Answer: B
Rationale: St. John’s Wort induces cytochrome P450 enzymes, reducing cyclosporine levels (
B), an immunosuppressant, risking graft rejection. Depression use (
A) is possible but less critical. Sodium (
C) and corticosteroids (D, E) are unrelated.
Choice E is a duplicate.
Question 2 of 5
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Question 3 of 5
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Question 4 of 5
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Question 5 of 5
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