HESI RN
Care Hope College RN HESI Pharmacology Questions
Extract:
Question 1 of 5
A patient with peptic ulcer disease has been prescribed cimetidine. Which statement made by the patient indicates the need for further instruction by the nurse?
Correct Answer: C
Rationale: Cimetidine should be taken with meals or immediately after, not 1 hour after antacids (
C), which interferes with absorption. Reducing smoking (
A) is insufficient; cessation is ideal. Lethargy (
B) and sexual dysfunction (
D) are valid monitoring points.
Question 2 of 5
The nurse is preparing to administer the anti-ulcer gastrointestinal agent sucralfate to a patient with peptic ulcer disease. What should be included in this patient’s care plan?
Correct Answer: B
Rationale: Sucralfate forms a protective barrier over ulcers and should be given on an empty stomach (
B), 1 hour before meals or at bedtime, for optimal efficacy. Once-daily dosing (
A) is incorrect; it’s typically 4 times daily. Candida infection (
C) and electrolyte imbalances (
D) are not associated with sucralfate.
Question 3 of 5
The nurse administers naloxone to a patient with opioid-induced respiratory depression. An hour later, the nurse finds the patient has a respiratory rate of 4 breaths/minute, oxygen saturation of 75%, and is unresponsive. What action should the nurse take?
Correct Answer: D
Rationale: Severe respiratory depression (4 breaths/min), hypoxia (75% SpO₂), and unresponsiveness require immediate CPR (
D) to restore circulation/oxygenation. A second naloxone dose (
A) may be needed but is secondary. Chest tubes (
B) are irrelevant. Glasgow scoring (
C) delays critical intervention.
Question 4 of 5
An adult patient at an outpatient clinic has been prescribed the antibiotic tetracycline HCI. What should the nurse include in the patient’s teaching plan?
Correct Answer: B
Rationale: Tetracycline causes photosensitivity, increasing sunburn risk, so sun protection (
B) is essential. Milk/antacids (
A) reduce absorption by chelating tetracycline. Orange juice (
C) contains calcium, impairing absorption. Weekly drug level checks (
D) are not required for tetracycline.
Question 5 of 5
A client with chemotherapy-induced nausea receives a prescription for metoclopramide. Which adverse effect is most important for the nurse to report?
Correct Answer: D
Rationale: Involuntary movements (
D), such as tardive dyskinesia, are a serious, potentially irreversible side effect of metoclopramide, requiring immediate reporting. Diarrhea (
A) and irritability (
B) are less severe. Nausea (
C) is the treated condition, not an adverse effect.