HESI Pharmacology Exam 2

Extract:

Question 1 of 5

A client who received a renal transplant three months ago is readmitted to the acute care unit with signs of graft rejection. While taking the client’s history, the nurse determines that the client has been self-administering St. John’s Wort, an herbal preparation, on the advice of a friend. Which information is most significant about this finding?

A. Ingestion of St. John’s Wort can reduce the client’s intake of sodium. B. Adding the herb can decrease the need for corticosteroids. C. The client probably used this herb to treat depression. D. St. John’s Wort can decrease plasma concentrations of cyclosporine.

Correct Answer: D

Rationale: St. John’s Wort induces liver enzymes, reducing cyclosporine levels, an immunosuppressant critical for preventing transplant rejection. This interaction directly contributes to graft rejection, making it the most significant finding. Sodium intake, corticosteroid needs, or depression treatment are less relevant to the acute issue.

Question 2 of 5

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Question 5 of 5

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A client who received a renal transplant three months ago is readmitted to the acute care unit with signs of graft rejection. While taking the client’s history, the nurse determines that the client has been self-administering St. John’s Wort, an herbal preparation, on the advice of a friend. Which information is most significant about this finding?

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HESI Pharmacology Exam 2 | Nurselytic

Nurselytic

HESI RN

HESI RN