HESI RN
Wgu RN HESI Pharmocology Questions
Extract:
Question 1 of 5
The nurse is providing instructions about a client's new medications. How should the nurse explain the purpose of probenecid, a uricosuric drug?
Correct Answer: D
Rationale: Probenecid increases uric acid excretion (
D) to treat gout. It doesn’t strengthen urine stream (
A), prevent kidney stones (
B), or reduce urinary pain (
C).
Question 2 of 5
The nurse administers naloxone to a client with opioid-induced respiratory depression. One hour later, nursing assessment reveals that the client has a respiratory rate of 4 breaths/minute, oxygen saturation of 75%, and is unable to be aroused. Which action should the nurse implement?
Correct Answer: B
Rationale: Severe respiratory depression (4 breaths/min), hypoxia (75% SpO₂), and unresponsiveness require immediate CPR (
B) to restore circulation/oxygenation (matches 55-Q19). Naloxone (
D) may be needed but is secondary. Chest tubes (
A) are irrelevant. Glasgow scoring (
C) delays intervention. Note: Provided answer D corrected to B.
Question 3 of 5
After receiving five doses of filgrastim, the nurse notes that the client's white blood cell count has increased from 2,500/mm3 (2.5 x 109/L) to 5,000/mm3 (5 x 109/L). Which action should the nurse implement?
Correct Answer: B
Rationale: Filgrastim stimulates white blood cell production. An increase to 5,000/mm3 (
B) indicates effectiveness (matches 55-Q11). Neutropenic precautions (
A) are unnecessary. Culture reports (
C) and vital signs (
D) don’t assess filgrastim’s efficacy.
Question 4 of 5
A client with anemia secondary to chronic kidney disease (CKD) started a prescription for epoetin alfa two months ago. Which client finding best indicates that the medication is effective?
Correct Answer: C
Rationale: Epoetin alfa stimulates red blood cell production. A hemoglobin of 12 g/dL (
C) is the most objective indicator of efficacy. Iron therapy (
A), energy levels (
B), and diet (
D) are supportive but less definitive.
Question 5 of 5
A young adult female client who is planning to become pregnant asks the nurse if she can continue taking isotretinoin for cystic acne. Which information is most important for the nurse to provide this client?
Correct Answer: D
Rationale: Isotretinoin is highly teratogenic, causing severe birth defects. Discontinuing 1 month before conception (
D) is critical. Breastfeeding (
A) and liver tests (
B) are secondary. Vitamin A (
C) avoidance is relevant but less urgent. Note: Explanation suggests D was intended.