HESI RN
Wgu RN HESI Pharmocology Questions
Extract:
Question 1 of 5
On admission, the healthcare provider prescribes a broad spectrum antibiotic for a client with a gram-negative infection. Before administering the first dose, it is most important for the nurse to implement which prescription?
Correct Answer: B
Rationale: Obtaining cultures (
B) before antibiotics identifies the specific bacteria and ensures effective treatment. Sodium/fluid monitoring (
A) is unrelated to antibiotics. Blood count/electrolytes (
C) don’t guide initial therapy.
Topical antibiotics (
D) are secondary.
Question 2 of 5
The nurse initiates an infusion of piperacillin-tazobactam for a client with a urinary tract infection. Five minutes into the infusion, the client reports not feeling well. Which client manifestation should the nurse identify as a reason to stop the infusion?
Correct Answer: D
Rationale: A scratchy throat (
D) may indicate anaphylaxis, requiring immediate cessation of piperacillin-tazobactam (matches 55-Q2). Hypertension (
A), bradycardia (
B), and pupillary constriction (
C) are not typical allergic response signs.
Question 3 of 5
The nurse is providing instructions about a client's new medications. How should the nurse explain the purpose of probenecid, a uricosuric drug?
Correct Answer: D
Rationale: Probenecid increases uric acid excretion (
D) to treat gout. It doesn’t strengthen urine stream (
A), prevent kidney stones (
B), or reduce urinary pain (
C).
Question 4 of 5
On admission, the healthcare provider prescribes a broad spectrum antibiotic for a client with a gram-negative infection. Before administering the first dose, it is most important for the nurse to implement which prescription?
Correct Answer: B
Rationale: Obtaining cultures (
B) before antibiotics identifies the specific bacteria and ensures effective treatment. Sodium/fluid monitoring (
A) is unrelated to antibiotics. Blood count/electrolytes (
C) don’t guide initial therapy.
Topical antibiotics (
D) are secondary.
Question 5 of 5
The nurse administers naloxone to a client with opioid-induced respiratory depression. One hour later, nursing assessment reveals that the client has a respiratory rate of 4 breaths/minute, oxygen saturation of 75%, and is unable to be aroused. Which action should the nurse implement?
Correct Answer: B
Rationale: Severe respiratory depression (4 breaths/min), hypoxia (75% SpO₂), and unresponsiveness require immediate CPR (
B) to restore circulation/oxygenation (matches 55-Q19). Naloxone (
D) may be needed but is secondary. Chest tubes (
A) are irrelevant. Glasgow scoring (
C) delays intervention. Note: Provided answer D corrected to B.