ATI LPN
Roach's Introductory Clinical Pharmacology 11th Edition
Chapter 15 Questions
Question 1 of 5
After teaching a group of nursing students about opioid antagonists, the instructor determines that the teaching was successful when the students identify which of the following as true about these drugs?
Correct Answer: A,D
Rationale: An opioid antagonist has a greater affinity for a cell receptor than an opioid agonist, and by binding to the cell receptor, it prevents a response to the opioid agonist.
Question 2 of 5
Which of the following would a nurse most likely be ordered to give to a client experiencing opioid-induced respiratory depression?
Correct Answer: A
Rationale: Naloxone is an opioid antagonist specifically developed to reverse respiratory depression associated with opioids. Naltrexone may also be used, but its primary use is in the treatment of alcohol dependence. Nalbuphine is an agonist-antagonist used for severe chronic pain. Naproxen is an NSAID. Nitroglycerin is used for angina.
Question 3 of 5
A nursing student is assigned to lead a class discussion on opioid antagonists. Which of the following would the student include as the mechanism by which opioid antagonists reverse the effects of opioid agonists?
Correct Answer: A,C
Rationale: Opioid agonists reverse the opioid effects by competing for the opiate receptor site and displacing the opioid drug.
Question 4 of 5
When administering an opioid antagonist, the nurse would expect reversal of which of the following opioid effects?
Correct Answer: A,B,C,D,E
Rationale: Opioid antagonists are not selective for reversal of specific adverse reactions occurring with the use of an opioid but will reverse all adverse reactions caused by opioids.
Question 5 of 5
A nurse determines that an opioid antagonist would most likely be needed in which situation?
Correct Answer: A,C,E
Rationale: Opioid antagonists are used for the treatment of the following: postoperative acute respiratory depression, reversal of opioid adverse effects (hypotension, bradycardia, etc.), and suspected acute opioid overdosage.