ATI LPN
Roach's Introductory Clinical Pharmacology 11th Edition
Chapter 18 Questions
Question 1 of 5
When describing the action of cholinesterase inhibitors to a class of nursing students, the instructor would include which of the following about their action?
Correct Answer: B,C
Rationale: Cholinesterase inhibitors act to increase the level of acetylcholine in the CNS by inhibiting its breakdown and slowing neural destruction.
Question 2 of 5
A client is prescribed donepezil. The nurse would assess the client for which of the following as a possible adverse reaction?
Correct Answer: A,B,C
Rationale: The nurse would assess the client for generalized adverse reactions to cholinesterase inhibitors like donepezil, which would include anorexia, nausea, vomiting, diarrhea, dizziness, and headache.
Question 3 of 5
When reviewing the medical record of a client who is prescribed galantamine, which of the following, if found, would the nurse identify as a contraindication for the drug requiring the nurse to contact the primary health care provider?
Correct Answer: A,C,D
Rationale: Galantamine is contraindicated in clients who are pregnant, are lactating, or have hepatic disease.
Question 4 of 5
Which condition would require the nurse to cautiously monitor a client who is receiving donepezil?
Correct Answer: B,C,D,E
Rationale: Cholinesterase inhibitors, like donepezil, are used cautiously in clients with renal or hepatic disease, bladder obstruction, seizure disorder, sick sinus syndrome, GI bleeding, history of ulcer disease, and asthma.
Question 5 of 5
A client is receiving donepezil. When reviewing the client's medication history, the nurse determines that the client is at increased risk for GI bleeding if the client is also taking which drug?
Correct Answer: A,D
Rationale: Use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as naproxen or ibuprofen, in combination with donepezil place the client at an increased risk for GI bleeding. Oxycodone, acetaminophen, and meperidine do not increase the client's risk.