ATI LPN
Roach's Introductory Clinical Pharmacology 11th Edition
Chapter 49 Questions
Question 1 of 5
After teaching a group of nursing students about antineoplastic drugs, the instructor determines that the teaching was successful when the students identify which of the following as being classified as a plant alkaloid?
Correct Answer: A,C,D,E
Rationale: Drugs that are derived from plant alkaloids include vinca alkaloids (vincristine), taxanes (paclitaxel), podophyllotoxins (etoposide), and camptothecin analogs (irinotecan). Capecitabine is an antimetabolite.
Question 2 of 5
A nurse is preparing to administer an antineoplastic drug that is classified as an antimetabolite. Which of the following might the nurse be preparing to give?
Correct Answer: A,B,C
Rationale: Antimetabolite drugs are substances that incorporate themselves into the cellular components during the S phase of cell division and include mercaptopurine (Purinethol), capecitabine (Xeloda), and fluorouracil (Adrucil). Etoposide and irinotecan are plant alkaloids.
Question 3 of 5
A client is receiving an alkylating agent. Which of the following would be used?
Correct Answer: B,D,E
Rationale: Alkylating agents make the cell a more alkaline environment, leading to cell damage. Alkylating agents include chlorambucil (Gliadel), cyclophosphamide (Cytoxan), and ifosfamide (Ifex). Bleomycin is classified as an antineoplastic antibiotic. Vinblastine is a plant alkaloid.
Question 4 of 5
The primary health care provider prescribes an antineoplastic antibiotic. The nurse identifies which of the following as a possibility?
Correct Answer: A,C,D
Rationale: Antineoplastic antibiotics have similar action to alkylating drugs and include bleomycin (Blenoxane), dactinomycin (Cosmegen), and daunorubicin (DaunoXome). Carboplatin is an alkylating agent. Busulfan is an alkyl sulfonate alkylating agent.
Question 5 of 5
A group of nursing students are reviewing antineoplastic drugs. The students demonstrate understanding of the information when they identify which of the following as cell cycle specific?
Correct Answer: B,C
Rationale: Plant alkaloids and antimetabolites are considered cell cycle-specific antineoplastic drugs. Alkylating agents and antineoplastic antibiotics are cell cycle-nonspecific agents. Retinoids are miscellaneous agents.