ATI LPN
Pharmacology and the Nursing Process 10th Edition Test Bank
Chapter 48 : Immunosuppressant Drugs Questions
Question 1 of 5
A patient has an order for cyclosporine (Sandimmune). The nurse finds that cyclosporine-modified product (Neoral) is available in the automated medication cabinet. Which action by the nurse is correct?
Correct Answer: D
Rationale: Cyclosporine-modified products (such as Neoral or Gengraf) are interchangeable with each other but are not interchangeable with Sandimmune. The nurse must obtain the Sandimmune form of the drug from the pharmacy.
Question 2 of 5
The nurse is preparing to administer an injection of monoclonal antibodies. Which additional drug will the nurse administer to minimize adverse reactions to the monoclonal antibodies?
Correct Answer: D
Rationale: The monoclonal antibodies such as basiliximab and daclizumab have a tendency to cause the allergy-like reaction known as cytokine release syndrome, which can be severe and even involve anaphylaxis. An injection of a corticosteroid, such as methylprednisolone, is recommended before the injection of monoclonal antibodies to avoid or alleviate this problem.
Question 3 of 5
When administering cyclosporine, the nurse notes that allopurinol is also ordered for the patient. What is a potential result of this drug interaction?
Correct Answer: B
Rationale: Allopurinol may cause increased levels of cyclosporine, and toxicity may result.
Question 4 of 5
The nurse is monitoring a patient who is receiving mycophenolate after an organ transplant. Which adverse effect is possible with mycophenolate therapy?
Correct Answer: B
Rationale: Common adverse effects of mycophenolate include hypertension, hypotension, peripheral edema, tachycardia, chest pain, and other effects.
Question 5 of 5
When monitoring a patient who is on immunosuppressant therapy with azathioprine, the nurse will monitor which laboratory results?
Correct Answer: B
Rationale: Leukopenia is a potential adverse effect of azathioprine therapy, so white blood cells need to be monitored.