ATI LPN
Pharmacology and the Nursing Process 10th Edition Test Bank
Chapter 47 : Biologic Response?Modifying and Antirheumatic Drugs Questions
Question 1 of 5
A patient is to receive filgrastim 5 mcg/kg/day. The patient weighs 176 pounds. Identify how many micrograms of medication this patient will receive each day.
Correct Answer: 400 mcg
Rationale: Convert pounds to kilograms: 176 ?· 2.2 = 80 kg. Calculate mcg/day for this patient: 5 mcg/kg/day ?? 80 kg = 400 mcg/day.
Question 2 of 5
A patient will be receiving aldesleukin (IL-2) (Proleukin), 600,000 IU/kg every 8 hours for 14 doses. The patient weighs 220 pounds. Identify how many IU of medication this patient will receive per dose.
Correct Answer: 60 million (60,000,000)
Rationale: . Convert pounds to kilograms: 220 ?· 2.2 = 100 kg. Calculate IU per dose for this patient: 600,000 IU/kg ?? 100 kg = 60,000,000 IU/dose.
Question 3 of 5
When monitoring a patient's response to interferon therapy, the nurse notes that the major dose-limiting factor for interferon therapy is which condition?
Correct Answer: B
Rationale: Patients who receive interferon therapy may experience flu-like symptoms: fever, chills, headache, malaise, myalgia, and fatigue. Fatigue is the major dose-limiting factor for interferon therapy. Patients taking high dosages become so exhausted that they are commonly confined to bed.
Question 4 of 5
A patient asks about his cancer treatment with monoclonal antibodies. The nurse tells him that which is the major advantage of treating certain cancers with monoclonal antibodies?
Correct Answer: C
Rationale: Monoclonal antibodies can target cancer cells specifically and have minimal effects on healthy cells, unlike conventional cancer treatments. As a result, there are fewer adverse effects when compared to traditional antineoplastic therapy. The other options are incorrect.
Question 5 of 5
During a patient's therapy with interleukins, the nurse monitors the patient for capillary leak syndrome. Which assessment finding, if present, would indicate this problem?
Correct Answer: D
Rationale: With capillary leak syndrome, the capillaries lose their ability to retain vital colloids, and these substances migrate into the surrounding tissues, resulting in massive fluid retention. As a result, heart failure, myocardial infarction, and dysrhythmias may occur. The other options do not reflect capillary leak syndrome.