ATI LPN
Pharmacology and the Nursing Process 10th Edition Test Bank
Chapter 46 : Antineoplastic Drugs Part 2: Cell Cycle?Nonspecific Drugs and Miscellaneous Drugs Questions
Question 1 of 5
When a patient is receiving cisplatin chemotherapy, the nurse will monitor for which adverse effects? (Select all that apply.)
Correct Answer: A,C,D,E
Rationale: Cisplatin can cause nephrotoxicity, ototoxicity, and peripheral neuropathy. Nephrotoxicity is manifested by rising blood urea nitrogen and creatinine levels; ototoxicity is manifested by tinnitus, hearing loss, and dizziness; peripheral neuropathy is manifested by numbness or tingling of the extremities.
Question 2 of 5
A patient will be receiving mitoxantrone, 12 mg/m?²/day every 3 weeks, as part of treatment for prostate cancer. Each dose is mixed into a 50-mL bag of D5W and needs to infuse over 15 minutes. The infusion pump delivers the dose at milliliters per hour. Identify the rate the nurse will set the pump to infuse.
Correct Answer: 200 mL/hr
Rationale: 15 minutes = 0.25 hour. 50 mL:0.25 hour::x mL:1 hour. (50 ?? 1) = (0.25 ?? x); 50 = 0.25x; x = 200 mL/hr.
Question 3 of 5
A patient is receiving doxorubicin as part of treatment for ovarian cancer. Which of these is a possible adverse effect of doxorubicin?
Correct Answer: A
Rationale: Decreased cardiac output related to the adverse effect of cardiotoxicity is a possible adverse effect related to doxorubicin because adverse effects of doxorubicin include liver and cardiovascular toxicities.
Question 4 of 5
When giving cisplatin, the nurse is aware that adverse effect of this drug is which condition?
Correct Answer: B
Rationale: Cisplatin may cause nephrotoxicity, and the patient's renal function must be monitored closely while on this drug. Ensuring hydration will help to prevent nephrotoxicity.
Question 5 of 5
The nurse is teaching a class about the various chemotherapy drugs. Which of these statements explains why alkylating drugs are also called 'cell cycle-nonspecific drugs'?
Correct Answer: B
Rationale: Cell cycle-nonspecific drugs kill cancer cells during any phase of the growth cycle, whereas cell cycle-specific drugs kill cancer cells during specific phases of the cell growth cycle.