ATI LPN
Pharmacology and the Nursing Process 10th Edition Test Bank
Chapter 42 : Antifungal Drugs Questions
Question 1 of 5
A patient with a severe fungal infection has orders for voriconazole. The nurse is reviewing the patient's medical record and would be concerned if which assessment finding is noted?
Correct Answer: B
Rationale: Voriconazole is contraindicated when co-administered with certain other drugs metabolized by the cytochrome P-450 enzyme 3A4 (e.g., quinidine) because of the risk for inducing serious cardiac dysrhythmias.
Question 2 of 5
During therapy with amphotericin B, the nurse will monitor the patient for known adverse effects that would be reflected by which laboratory result?
Correct Answer: A
Rationale: The nurse needs to monitor for hypokalemia, a possible adverse effect of amphotericin B. A serum potassium level of 2.7 mEq/L indicates hypokalemia, which requires attention.
Question 3 of 5
A patient has received a prescription for a 2-week course of antifungal suppositories for a vaginal yeast infection. She asks the nurse if there is an alternative to this medication, saying, 'I don't want to do this for 2 weeks!' Which is a possibility in this situation?
Correct Answer: C
Rationale: A single oral dose of fluconazole may be used to treat vaginal candidiasis.
Question 4 of 5
A patient is taking nystatin oral lozenges to treat an oral candidiasis infection resulting from inhaled corticosteroid therapy for asthma. Which instruction by the nurse is appropriate?
Correct Answer: B
Rationale: Nystatin may be given orally in the form of lozenges, or troches, which need to be slowly and completely dissolved in the mouth for optimal effects; tablets are not to be chewed or swallowed whole. Patients taking an inhaled corticosteroid must rinse their mouths with water thoroughly after taking the inhaler.
Question 5 of 5
The nurse is administering an amphotericin B infusion. Which actions by the nurse are appropriate? (Select all that apply.)
Correct Answer: B,D,E,F
Rationale: If the patient develops tingling and numbness in the extremities (paresthesias), discontinue the drug immediately. An infusion pump is necessary for the infusion, and the nurse will monitor the IV site for signs of phlebitis and infiltration. Premedication to reduce the adverse effects of fever, malaise, and nausea may be ordered. The IV solution must be clear and without precipitates; and muscle weakness, not twitching, may indicate hypokalemia. The medication must be administered at the rate recommended and stopped, not slowed, if adverse reactions occur.