ATI LPN
Pharmacology and the Nursing Process 10th Edition Test Bank
Chapter 31 : Thyroid and Antithyroid Drugs Questions
Question 1 of 5
Levothyroxine has been prescribed for a patient with hypothyroidism. The nurse reviews the patient's current medications for potential interactions. Which of these drugs or drug classes interact with levothyroxine? (Select all that apply.)
Correct Answer: A,B,D,F
Rationale: Levothyroxine interacts with phenytoin, estrogens, warfarin, and iron supplements, which can alter its absorption or metabolism, affecting thyroid function. Beta blockers and penicillins do not have significant interactions.
Question 2 of 5
The nurse is giving morning medications. The Medication Administration Record has an order for levothyroxine, 88 mcg PO. The drug-dispensing cabinet contains levothyroxine tablets in milligram strengths instead of micrograms. Calculate the milligram equivalent dose of 88 mcg.
Correct Answer: 0.088 mg
Rationale:
To calculate: 1000 mcg/1 mg = 88 mcg/x mg. Cross-multiply: (1000 * x) = (1 * 88); 1000x = 88; x = 88/1000 = 0.088 mg.
Question 3 of 5
A patient, newly diagnosed with hypothyroidism, receives a prescription for a thyroid hormone replacement drug. The nurse assesses for which potential contraindication to this drug?
Correct Answer: D
Rationale: Thyroid hormone replacement is contraindicated in recent myocardial infarction due to increased cardiac workload, which could exacerbate heart conditions. Infection, diabetes, and liver disease are not absolute contraindications.
Question 4 of 5
A patient with hypothyroidism is given a prescription for levothyroxine. When the nurse explains that this is a synthetic form of the thyroid hormone, he states that he prefers to receive more 'natural' forms of drugs. What will the nurse explain to him about the advantages of levothyroxine?
Correct Answer: D
Rationale: Levothyroxine's long half-life allows for convenient once-daily dosing, improving adherence compared to natural forms. It does not necessarily have stronger effects, lower cost, or fewer GI adverse effects.
Question 5 of 5
The order reads, 'Give levothyroxine, 200 mg, PO once every morning.' Which action by the nurse is correct?
Correct Answer: D
Rationale: Levothyroxine is dosed in micrograms (mcg), not milligrams (mg). A 200 mg dose would be a thousandfold overdose, so the nurse must question the order to ensure it is corrected to 200 mcg.