ATI LPN
Pharmacology and the Nursing Process 10th Edition Test Bank
Chapter 27 : Antilipemic Drugs Questions
Question 1 of 5
The nurse will monitor for myopathy (muscle pain) when a patient is taking which class of antilipemic drugs?
Correct Answer: B
Rationale: HMG-CoA reductase inhibitors (statins) can cause myopathy, including muscle pain, which may progress to rhabdomyolysis. Patients should report unexplained muscle pain immediately. Other classes do not commonly cause myopathy.
Question 2 of 5
When teaching a patient who is beginning antilipemic therapy about possible drug-food interactions, the nurse will discuss which food?
Correct Answer: B
Rationale: Grapefruit juice inhibits CYP3A4, which metabolizes statins, potentially increasing statin levels and toxicity risk, including rhabdomyolysis. Bran, licorice, and dairy products do not significantly interact with antilipemic drugs.
Question 3 of 5
The nurse is conducting a class about antilipemic drugs. The antilipemic drug ezetimibe works by which mechanism?
Correct Answer: D
Rationale: Ezetimibe selectively inhibits cholesterol absorption in the small intestine, reducing circulating cholesterol levels. It does not inhibit HMG-CoA reductase, prevent bile acid resorption, or activate lipins.
Question 4 of 5
Antilipemic drug therapy is prescribed for a patient, and the nurse is providing instructions to the patient about the medication. Which instructions will the nurse include? (Select all that apply.)
Correct Answer: B,C,D
Rationale: Instructions include eating raw vegetables and fruit to prevent constipation, reporting bleeding or jaundice (indicating liver issues), and reporting muscle pain (potential myopathy). Antilipemics have frequent drug interactions, and fluid intake should be encouraged, not limited. Taking with food may reduce GI distress, not before/after meals.
Question 5 of 5
The medication order reads, 'Give simvastatin 30 mg daily at bedtime, PO.' The medication is available in 20-mg tablets. Identify how many tablets the nurse will administer to the patient.
Correct Answer: 1.5
Rationale:
To calculate: 20 mg/1 tablet = 30 mg/x tablets. Cross-multiply: (20 * x) = (1 * 30); 20x = 30; x = 30/20 = 1.5 tablets.