ATI LPN
Pharmacology and the Nursing Process 10th Edition Test Bank
Chapter 8 : Gene Therapy and Pharmacogenomics Questions
Question 1 of 5
The nurse is preparing a class on gene therapy for a group of students. Which statements about gene therapy are true?
Correct Answer: A,C,D,E
Rationale: Gene therapy may include: Replacing a mutated gene with a healthy copy of the gene; introducing a new gene into the body to help fight a disease; inactivating a mutated gene that is functioning improperly. In addition, the FDA must review and approve all human clinical genetic trials. Gene therapy does not include creating new genes.
Question 2 of 5
A patient will be receiving famotidine 20 mg at bedtime. A liquid form is ordered because the patient cannot swallow pills or capsules; the concentration of the liquid is 40 mg/5 mL. How many milliliters will the patient receive per dose?
Correct Answer: 2.5 mL
Rationale: 40 mg : 5 mL :: 20 mg : x mL; (40 * x) = (5 * 20); 40x = 100; x = 2.5 mL/dose.
Question 3 of 5
The nurse is reviewing the applications of gene therapy. Which drug is manufactured as a result of indirect gene therapy?
Correct Answer: C
Rationale: A recombinant form of human insulin is one of the most widespread uses of indirect gene therapy. Other examples include hormones, vaccines, antitoxins, and monoclonal antibodies. The other options listed are not examples of drugs manufactured by indirect gene therapy.
Question 4 of 5
The nurse is discussing gene therapy in a continuing education class. Which is the best definition of eugenics?
Correct Answer: C
Rationale: Eugenics is the intentional selection of genotypes, before birth, that are considered more desirable than others, and it is a major ethical issue concerning gene therapy. The other options do not describe eugenics.
Question 5 of 5
The nurse is explaining the Human Genome Project to colleagues. Which of these is the main purpose of the Human Genome Project?
Correct Answer: D
Rationale: The Human Genome Project was undertaken to describe in detail the entire genome of a human being. The other options do not describe the Human Genome Project.