ATI LPN
Pharmacology and the Nursing Process 10th Edition Test Bank
Chapter 8 : Gene Therapy and Pharmacogenomics Questions
Question 1 of 5
The nurse is asking a patient about his family history as part of an assessment. Which component is included in an effective family history?
Correct Answer: B
Rationale: The family history is most effective if it covers at least three generations and includes the current and past health status of each family member. The other options are incorrect.
Question 2 of 5
The nurse is reviewing principles of genetics. Which of these is a long strand of DNA that is contained within the nuclei of cells?
Correct Answer: D
Rationale: A chromosome is a long strand of DNA that is contained in the nuclei of cells. DNA molecules, in turn, act as the template for the formation of RNA molecules, from which proteins are made. The other answers are incorrect.
Question 3 of 5
The nurse is asking a patient about his drug history, and the patient states, - Whenever I take any strong pain medications, I usually sleep for hours, I have no idea why that happens!! The nurse considers that which of these is true about this patient's statement?
Correct Answer: B
Rationale: It is important to inquire about any unusual reactions to a drug - on the part of the patient, family members, significant others, and/or caregivers. An unusual or other than expected reaction to a drug in family members may point to a difference in the patient's ability to metabolize certain drugs. Genetic factors may alter a patient's metabolism of a particular drug, resulting in either increased or decreased drug action. The other statements are not correct.
Question 4 of 5
The nurse is performing an assessment of a patient. Which assessment findings may indicate a higher risk for genetic disorders?
Correct Answer: B,D,E
Rationale: The nurse should assess for factors that may indicate a risk for genetic disorders. A few examples of factors that may indicate a risk for genetic disorders are a higher incidence of a particular disease or disorder in the patient's family than in the general population; diagnosis of a disease in family members at an unusually young age; or diagnosis of a family member with an unusual form of cancer or with more than one type of cancer. The options regarding heart disease at 60 years of age and cerebral vascular accident at 78 years of age are not factors that indicate a higher risk for genetic disorders.
Question 5 of 5
The nurse is preparing a class on gene therapy for a group of students. Which statements about gene therapy are true?
Correct Answer: A,C,D,E
Rationale: Gene therapy may include: Replacing a mutated gene with a healthy copy of the gene; introducing a new gene into the body to help fight a disease; inactivating a mutated gene that is functioning improperly. In addition, the FDA must review and approve all human clinical genetic trials. Gene therapy does not include creating new genes.