Chapter 24: The Child with Hematologic or Immunologic Dysfunction - Nurselytic

Questions 20

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Chapter 24 : The Child with Hematologic or Immunologic Dysfunction Questions

Question 1 of 5

Iron overload is a side effect of chronic transfusion therapy. What treatment assists in minimizing this complication?

Correct Answer: B

Rationale: Deferoxamine infusions chelate and excrete excess iron, minimizing overload from chronic transfusions. Magnetic therapy is ineffective, hemoglobin electrophoresis is diagnostic, and washing RBCs removes other components, not iron.

Question 2 of 5

In which condition are all the formed elements of the blood simultaneously depressed?

Correct Answer: A

Rationale: Aplastic anemia involves bone marrow failure, depressing all blood elements (RBCs, WBCs, platelets). Sickle cell anemia affects hemoglobin, thalassemia major impacts hemoglobin chain production, and iron deficiency reduces RBC size and hemoglobin, not all elements.

Question 3 of 5

For children who do not have a matched sibling bone marrow donor, the therapeutic management of aplastic anemia includes what intervention?

Correct Answer: D

Rationale: Immunosuppressive therapy (e.g., antilymphocyte globulin, cyclosporine) treats aplastic anemia, likely an autoimmune condition, improving prognosis. Antibiotics treat infections, not the condition; antiretrovirals and iron are irrelevant to aplastic anemia management.

Question 4 of 5

The regulation of red blood cell (RBC) production is thought to be controlled by which physiologic factor?

Correct Answer: B

Rationale: Tissue hypoxia triggers the kidneys to release erythropoietin, stimulating bone marrow to produce RBCs. Hemoglobin levels indirectly influence this through oxygen delivery, reticulocyte count monitors production, and RBC numbers don?t directly control production.

Question 5 of 5

What physiologic defect is responsible for causing anemia?

Correct Answer: D

Rationale: Anemia is defined by reduced RBCs or hemoglobin, leading to decreased oxygen-carrying capacity. Increased viscosity occurs with too many cells, a depressed hematopoietic system or abnormal hemoglobin may contribute, but the core defect is reduced oxygen delivery.

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